Circulating Biomarkers in Young Individuals with Low Peak FEV1

It is now well established that there is a range of lung function tralectories throughout the life course (1, 2). Specifically, 4-12% of young adults in the general population never achieve normal peak lung function, as determined by FEV, measurement (3). These individuals are at higher risk of developing chronic obstructive pulmonary disease (COPD) in adulthood (4), suffer a higher prevalence and a decade earlier incidence of cardiovascular and metabolic disorders, and die prematurely (3, 5). The biological mechanisms underlying these observations are unknown.

Autores: Nuria Olvera 1,2, Sandra Casas 1,2, Judith M. Vonk 3,4, Tamara Garcia 1,2, H. Marike Boezen 3,4, Maarten van den Berge 4, Alvar Agusti 1,2,5,6, and Rosa Faner 1,2,5*

Puedes leer el artículo completo aquí: https://www.atsjournals.org/doi/abs/10.1164/rccm.202205-0855LE?role=tab

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Telomere length in patients with bronchiectasis

This study investigates telomere length (TL) in bronchiectasis patients, comparing them to COPD patients and healthy controls. Findings show no significant TL reduction in bronchiectasis compared to controls, but a trend towards shorter TL in idiopathic cases. Further research is needed to understand TL’s role in bronchiectasis.

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Recuerda que puedes acceder a varios enlaces a artículos dentro de la categoría EPOC en esta web. También puedes acceder otros enlaces en el Listado de Artículos de la Cátedra de Salud Respiratoria.

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