Some patients with COPD suffer frequent exacerbations (FE). We hypothesised that their systemic proteomic profile would be different from that of non-frequent exacerbators (NFE).
This study shows that patients with f-ILDs several immune populations in circulating blood, skewed toward an aged and exhausted immune profile, relate to lung function impairment at diagnosis, and that PPF is associated with an increased cytotoxic immune response.
Pulmonary vascular reactivity in FGR using computational modelling and machine learning analysis of fetal Doppler waveforms
COPD results from gene-environment interactions over the lifetime. These interactions are captured by epigenetic changes
La LSC es líder en ciencia respiratoria básica y traslacional, constituyendo un evento clave para investigadores emergentes en respiración que buscan impulsar su carrera.
La Fundación La Marató de TV3 organiza el evento anual «La Marató 2024», que busca recaudar fondos para la investigación científica de enfermedades que no tienen cura
To investigate it, we calculated immune signatures with Gene Set Variation Analysis (GSVA) and applied them to the lung transcriptome followed by unbiased cluster analysis of GSVA immune-enrichment scores, in 109 IPF patients from the Lung Tissue Research Consortium (LTRC)
«Biologics for COPD — Finally Here» highlighted as one of the notable articles among the featured selections on NEJM Notable Articles of 2023
Del autor de El emperador de todas las enfermedades, ganador del Premio Pulitzer, y El gen, bestseller número uno del New York Times, llega su libro más espectacular hasta el momento, una exploración de la medicina y nuestra nueva y radical capacidad para manipular las células.
Magnifica historia, biográfica y científica, del descubrimiento e implicaciones del método CRISPr que valió el premio Nobel a sus dos descubridores.
