Early diagnosis and treatment of COPD seems to be of paramount importance, and efforts are being devoted to the diagnosis of pre-COPD and COPD in young individuals…
Complex diseases may be defined by combining two or more characteristics, ‘but independent of the characteristics used, once a definition is agreed on, itis practical to adopt a nomenclature that uses names and terms to classify subgroups within the disease than share similar characteristics. It follows that the definition and classification of diseases can and should change over time.
The presence of CBI by any PPM, and one or more PA isolation, were independently associated with FEV1 decline in patients with COPD.
Clinical trials evaluating the management of acute exacerbations of COPD assess heterogeneous outcomes, often omitting those that are clinically relevant or more important to patients. (…)
