Differential Diagnosis of Suspected COPD Exacerbations in the Acute Care Setting: Best Practice
enero 26, 2023
Approximately 25% and 65% of patients hospitalized for an ECOPD die within 1 and 5 years, respectively.
Approximately 25% and 65% of patients hospitalized for an ECOPD die within 1 and 5 years, respectively.
COPD is a complex and heterogeneous disease characterized by chronic airway inflammation. The latter may alter airway antimicrobial defense systems and therefore favor the colonization of the bronchial mucosa by potentially pathogenic microorganisms.
The European Respiratory Journal is voluntarily reviewed. We are most grateful for the hard work and dedication of all those who reviewed articles for the ERJ in 2022.
«Chronic airway diseases such as asthma and chronic obstructive pulmonary disease are prevalent and complex conditions that often coexist in the same patient. To address this complexity in clinical practice, and to move forward toward personalized and precision…»
Early diagnosis and treatment of COPD seems to be of paramount importance, and efforts are being devoted to the diagnosis of pre-COPD and COPD in young individuals…
Complex diseases may be defined by combining two or more characteristics, ‘but independent of the characteristics used, once a definition is agreed on, itis practical to adopt a nomenclature that uses names and terms to classify subgroups within the disease than share similar characteristics. It follows that the definition and classification of diseases can and should change over time.
The presence of CBI by any PPM, and one or more PA isolation, were independently associated with FEV1 decline in patients with COPD.
Clinical trials evaluating the management of acute exacerbations of COPD assess heterogeneous outcomes, often omitting those that are clinically relevant or more important to patients. (…)