Explore the history of COPD and the evolution of disease concepts, treatment strategies, patient outcomes, pulmonary rehabilitation and clinical management.
Comparison of COPD exacerbator classification systems (GOLD E vs Frequent Exacerbator) using proteomics and metabolomics to identify biological differences and biomarkers.
The ROME proposal for COPD exacerbations classification offers a new approach to assess severity and predict outcomes, improving clinical decision-making
Lessons from the ANTES B+ study highlighting challenges in COPD clinical trials, recruitment difficulties, and implications for future study design.
Patients with COPD prioritise chronic symptoms and functional impact as key outcomes in COPD exacerbation treatment trials.
Observational study shows bronchiectasis symptoms independently predict exacerbations and identify patients who benefit from macrolide therapy, even with few prior episodes.
Airway mucous plugging is associated with exacerbations, lung function decline, and mortality in COPD, asthma, and bronchiectasis. Identifying it as a treatable trait may improve patient outcomes through airway clearance techniques and pharmacological strategies.
