This study shows that patients with f-ILDs several immune populations in circulating blood, skewed toward an aged and exhausted immune profile, relate to lung function impairment at diagnosis, and that PPF is associated with an increased cytotoxic immune response.
Pulmonary vascular reactivity in FGR using computational modelling and machine learning analysis of fetal Doppler waveforms
COPD results from gene-environment interactions over the lifetime. These interactions are captured by epigenetic changes
La LSC es líder en ciencia respiratoria básica y traslacional, constituyendo un evento clave para investigadores emergentes en respiración que buscan impulsar su carrera.
Lung-function development can be altered by several host and environmental factors during the life course. As a result, a range of lung-function trajectories exist in the population.
Our understanding of the pathogenesis of COPD has changed very significantly over the past few years.
A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as «Aging (Albany NY)» and «Aging-US» by Web of Science) Volume 15, Issue 14, entitled, «Human senescent fibroblasts trigger progressive lung fibrosis in mice.»
Most patients with chronic obstructive pulmonary disease (COPD) have at least one additional, clinically relevant chronic disease. Those with the most severe airflow obstruction will die from respiratory failure, but most patients with COPD die from non-respiratory disorders, particularly cardiovascular diseases and cancer.
The role of the immune response in the pathogenesis of idiopathic pulmonary fibrosis (IPF) remains controversial.
It is now well established that there are different life-long lung function trajectories in the general population, and that some are associated with better or worse health outcomes.
