COPD is a complex and heterogeneous disease characterized by chronic airway inflammation. The latter may alter airway antimicrobial defense systems and therefore favor the colonization of the bronchial mucosa by potentially pathogenic microorganisms.
The European Respiratory Journal is voluntarily reviewed. We are most grateful for the hard work and dedication of all those who reviewed articles for the ERJ in 2022.
In conclusion, these observations show, for the first time to our knowledge, that being born SGA at term tracks into a shorter height in early adulthood but does not result in reduced lung function for that reduced height.
«Chronic airway diseases such as asthma and chronic obstructive pulmonary disease are prevalent and complex conditions that often coexist in the same patient. To address this complexity in clinical practice, and to move forward toward personalized and precision…»
The objectives of this task force were to review the terminology, definition, characteristics, pathophysiology, and research priorities of CPFE and to explore whether CPFE is a syndrome.
Early diagnosis and treatment of COPD seems to be of paramount importance, and efforts are being devoted to the diagnosis of pre-COPD and COPD in young individuals…
Complex diseases may be defined by combining two or more characteristics, ‘but independent of the characteristics used, once a definition is agreed on, itis practical to adopt a nomenclature that uses names and terms to classify subgroups within the disease than share similar characteristics. It follows that the definition and classification of diseases can and should change over time.
COPD and lung cancer are highly prevalent causes of morbidity and mortality, worldwide. Their combined presence poses important challenges to diagnosis, treatment, and prognosis.
Este artículo recoge una serie de reflexiones sobre posibles oportunidades de mejora en el ámbito de consultas externas basadas en la experiencia de un grupo amplio de profesionales sanitarios que, en su doble vertiente de pacientes y profesionales, aportan su visión personal sobre el tema.
Clinical trials evaluating the management of acute exacerbations of COPD assess heterogeneous outcomes, often omitting those that are clinically relevant or more important to patients. (…)
