High prevalence of obstructive sleep apnea in patients with Long-COVID

Sleep apnea in Long-COVID
Sleep apnea is highly prevalent in Long-COVID patients. Sleep studies may help identify treatable causes of persistent symptoms and insomnia.

Sleep Apnea in Long-COVID Patients

Long-COVID and Shared Sleep-Related Symptoms

Long-COVID (LC) is defined as the persistence of symptoms 12 weeks after the acute COVID infection not explained by any other alternative diagnosis. Its pathophysiology is poorly understood.

Obstructive Sleep Apnea (OSA) shares several clinical manifestations with LC, such as fatigue and low-quality sleep, however, thus far, their potential coexistence has been poorly addressed.

Prevalence of OSA in Long-COVID

We studied 73 patients with LC. Median AHI was 17.2 (24.14) events/h with a proportion of mild (27.4%), moderate (24.6%) and severe OSA (31.5%).

Objective questionnaires identified poor sleep quality and fatigue as the most prevalent symptoms and daytime sleepiness as the least prevalent.

Clinical Implications for Sleep Assessment

In this single-center, clinic-based LC cohort, OSA diagnosed by in-lab PSG was highly common.

Given that OSA is treatable, a sleep study should be considered in LC patients even in the absence of daytime sleepiness or in the presence of insomnia.

Authors

Victoria Mery, Nuria Albacar, Monica Matute-Villacís, Mireia Dalmases, Oriol Sibila, Àlvar Agustí, Cristina Embid

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Fecha de publicación

June 2026

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